- Mouse Anti-CDX2/Caudal Type Homeobox 2 Antibody
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- MBS4380781
- 0.02 mg (With BSA & Azide at 0.2mg/ml)
- Monoclonal
- Human
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml
- Immunohistochemistry (IHC) Paraffin
- Mouse
- 40kDa
- CDX2/Caudal Type Homeobox 2
- Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
- caudal type homeobox 2
- CDX2/AS, CDX3, CDX-3
- Unconjugated
- IgG1 kappa
- CDX2/2214
Specifications/Features
The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoidsand is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma.However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary